Ibuprofen vs. Aspirin: Comparing NSAIDs for Crises de migraine

Ibuprofen vs. Aspirin: Comparing NSAIDs for Crises de migraine


As someone who frequently experiences debilitating crises de migraine, I understand the importance of finding effective relief. Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) such as ibuprofen and aspirin have been widely used for migraine treatment. In this article, we will delve deeper into the comparison between ibuprofen and aspirin in terms of their efficacy, mechanisms of action, potential side effects, and factors to consider when choosing the right NSAID for your crises de migraine.

Understanding NSAIDs

NSAIDs, or Non-Steroidal Anti-Inflammatory Drugs, are a class of medications commonly used for their pain-relieving, anti-inflammatory, and fever-reducing properties. When it comes to crises de migraine, ibuprofen and aspirin are two commonly used NSAIDs that can provide relief.


Ibuprofen is a readily available NSAID that can be purchased over-the-counter. It is known for its analgesic (pain-relieving) and anti-inflammatory effects. Many individuals rely on ibuprofen to alleviate their migraine symptoms due to its effectiveness and accessibility.

The mechanism of action for ibuprofen involves inhibiting the production of prostaglandins by blocking the enzyme cyclooxygenase (COX). By reducing the production of prostaglandins, ibuprofen helps to alleviate pain, reduce inflammation, and potentially lessen the severity of migraine symptoms.

Various studies have supported the use of ibuprofen for crises de migraine. For example, a study published in the Journal of the American Medical Association (JAMA) found that ibuprofen was effective in reducing the severity of crises de migraine and improving associated symptoms such as nausea and sensitivity to light.

Furthermore, ibuprofen is available in different formulations, including tablets, capsules, and liquids. This variety allows individuals to choose the most convenient and effective option for their crises de migraine.


Aspirin, also known as acetylsalicylic acid, is another commonly used NSAID. While it is not specifically marketed for crises de migraine, many individuals find aspirin to be effective in providing relief from crises de migraine.

Similar to ibuprofen, aspirin works by inhibiting the synthesis of prostaglandins. Additionally, aspirin possesses antiplatelet properties, meaning it can also help prevent blood clot formation. This dual mechanism of action makes aspirin particularly beneficial for individuals who experience crises de migraine with aura, as the antiplatelet effect may help reduce the risk of stroke.

Comparative studies have shown that aspirin is comparable in efficacy to other NSAIDs commonly used for crises de migraine. In a study published in the journal Headache, aspirin was found to be as effective as other NSAIDs in providing relief for acute crises de migraine.

Aspirin is available in low-dose formulations, primarily marketed for cardiovascular health. Some individuals may find these low-dose aspirin tablets to be suitable for managing their crises de migraine.

Side Effects and Safety Considerations

While both ibuprofen and aspirin are generally considered safe and well-tolerated, it is important to be aware of their potential side effects and safety considerations.

Some potential side effects of ibuprofen include stomach upset, heartburn, gastrointestinal bleeding, and an increased risk of cardiovascular events. Individuals with a history of gastrointestinal ulcers or bleeding, high blood pressure, kidney problems, and heart disease should exercise caution when using ibuprofen.

Aspirin, on the other hand, can also cause gastrointestinal upset, heartburn, and gastrointestinal bleeding. It is especially important for individuals with asthma, blood clotting disorders, peptic ulcers, or those taking blood-thinning medications to use aspirin with caution.

When choosing between ibuprofen and aspirin for your crises de migraine, it is essential to consider your existing health conditions, any medication interactions, and consult with your healthcare professional to ensure the appropriate choice for you.

Choosing the Right NSAID for Your Crises de Migraine

When it comes to selecting the most efficacious NSAID for your crises de migraine, several factors should be taken into consideration:

  • Individual response: Pay attention to how your body responds to each medication. Some individuals may find ibuprofen more effective, while others may prefer aspirin.
  • Allergies or sensitivities: If you have any known allergies or sensitivities to specific NSAIDs, it is important to avoid them and choose an alternative that is safe for you.
  • Overall health condition: Consider your overall health and any existing medical conditions that may influence your choice of NSAID.

Ultimately, the choice between ibuprofen and aspirin for crises de migraine may vary from person to person. It is recommended to consult with a healthcare professional before making any decisions regarding medication choices. Your healthcare provider can help you weigh the benefits and risks of each NSAID and provide personalized advice based on your specific situation.

Frequently Asked Questions

1. Can NSAIDs completely cure crises de migraine?

No, NSAIDs provide symptomatic relief and cannot completely cure crises de migraine. However, they can effectively reduce pain and other associated symptoms during crises de migraine.

2. Can I take ibuprofen and aspirin together for crises de migraine?

It is generally not recommended to take ibuprofen and aspirin together unless specifically advised by a healthcare professional. Both medications belong to the same class of drugs and can have similar effects and side effects.

3. Are there any alternatives to ibuprofen and aspirin for migraine relief?

Yes, there are other NSAIDs, such as naproxen and diclofenac, which can be prescribed by your healthcare professional for migraine relief. Additionally, there are specific migraine medications available, such as triptans and ergots.

4. Can NSAIDs be used for all types of crises de migraine?

NSAIDs can be effective for treating crises de migraine with or without aura. However, individuals with specific medical conditions or contraindications may need to avoid or use NSAIDs with caution.

5. How long does it take for NSAIDs to work for crises de migraine?

The onset of action for NSAIDs varies, but it is generally recommended to take them at the first signs of a migraine attack for maximum effectiveness. The time it takes for relief to be felt can vary from person to person.

6. Can I use NSAIDs for long-term migraine prevention?

No, NSAIDs are not typically used for long-term migraine prevention. They are more commonly used for acute symptom relief during crises de migraine. Consult your healthcare professional for appropriate long-term prevention options.

7. Are there any age restrictions for using ibuprofen and aspirin for crises de migraine?

Both ibuprofen and aspirin have age restrictions for use. Ibuprofen is generally safe for children aged 6 months and older, while aspirin should be avoided in individuals under 18 years of age due to the risk of Reye’s syndrome.

8. Can NSAIDs cause rebound headaches?

Rebound headaches can occur with frequent and excessive use of NSAIDs. It is important to follow the recommended dosage and frequency guidelines provided by your healthcare professional or indicated on the medication packaging.

9. Can NSAIDs interact with other medications I’m taking?

Yes, NSAIDs can interact with certain medications, including blood thinners, certain antidepressants, and other NSAIDs. It is essential to inform your healthcare professional about all the medications you are taking to avoid potential interactions.

10. Can lifestyle changes reduce the need for NSAIDs in managing crises de migraine?

Yes, adopting a healthy lifestyle, managing stress, getting regular exercise, and identifying and avoiding migraine triggers can all contribute to reducing the frequency and severity of crises de migraine, potentially reducing the reliance on NSAIDs.


When it comes to managing your crises de migraine effectively, choosing the right NSAID plays a vital role. Both ibuprofen and aspirin have been widely used for migraine relief. Understanding their mechanisms of action, efficacy, potential side effects, and considering personal factors can help you make an informed decision. Remember, it is essential to consult with your healthcare professional to ensure the most suitable NSAID choice for your crises de migraine. By finding the right NSAID, you can experience significant relief and improve your overall quality of life.

Jenny from Migraine Buddy

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